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pentobarbital will lessen the level or result of abemaciclib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Coadministration of abemaciclib with powerful CYP3A4 inducers lessens plasma focus of abemaciclib and its metabolites.When the dose of the concomitant CYP3A4 inducer can't be diminished or di

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